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Research guide5 min read

Peer review, preprints and retractions

Detail level

Journals usually certify research through peer review before publishing it. Some studies are posted publicly earlier as preprints, before peer review, and some published papers are later retracted. Knowing these states protects you from relying on findings that are not yet certified or have been withdrawn.

According to the NLM, journals retract articles because of major errors or data that are unverified or cannot be reproduced, and the NLM links the retraction notice to the original article in PubMed, without distinguishing between retraction for an honest error and retraction for misconduct or plagiarism. A retracted article is labelled with the publication type "Retracted Publication".

A retraction may be preceded by an "Expression of Concern" written by a journal editor about the integrity of an article, who then investigates and announces the outcome, which may end in retraction. Corrections acknowledge specific errors and indicate where they are. In September 2023 Crossref acquired the Retraction Watch database and made it publicly available; it is updated every working day, and the Study Reader in this encyclopedia uses it.

The core idea

Preprints are complete, publicly available versions of scientific research that have not yet been approved through peer review; approval through peer review is the key difference between them and an article published in a journal.

A retraction is a formal announcement that a published article, in whole or in part, is withdrawn, by its authors or by an authorised body, and journals retract articles because of major errors or data that are unverified or cannot be reproduced.

Why it matters to you

Any aspect of research in a preprint, including the results and conclusions, may change as a result of peer review; so it is not treated as a final result.

The NLM links the retraction notice to the original article so the reader knows it was retracted.

Sources13

States a study can be in

Preprint: available before peer review, and carries in PMC a notice that it is a preprint that has not yet undergone peer review in a journal. Its results and conclusions may change after peer review, and the authors may publish updated versions of it.

Article published after peer review: approved by a journal through peer review, but it remains open to debate and correction.

Erratum: a formal acknowledgement by the publisher, editor or author of an error in a published article, specifying where it is.

Expression of Concern: a notice from the editor about the integrity of an article, followed by an investigation that may end in retraction.

Retracted article: classified in PubMed with the publication type "Retracted Publication", and the retraction notice itself is classified "Retraction Notice", and each is linked to the other.

How to check a study’s status

Enter a DOI in the Study Reader: it checks the update notices linked to the article in Crossref, which includes Retraction Watch data, and the publication types in Europe PMC.

In PubMed, a retracted article appears with the publication type "Retracted Publication" and a link to the retraction notice.

Common pitfalls

Citing a preprint as if it were a final peer-reviewed result.

Assuming every retraction means fraud: the NLM does not distinguish in its linking between retraction for an honest error and retraction for misconduct or plagiarism.

Sources13

Limits of this page

The data on corrections and expressions of concern in Retraction Watch are less comprehensive than the retraction data, according to Crossref.

The absence of a retraction notice does not guarantee that a study is sound or strong; it only means that no retraction has been recorded in the sources checked.

Sources4

Common questions

Is a preprint incorrect research?

Not necessarily; it is complete research made publicly available that has not yet been approved through peer review, and many are later submitted to journals, but their results and conclusions may change after peer review.1

Why is research retracted?

According to the NLM, journals retract articles because of major errors or data that are unverified or cannot be reproduced, and the cause may be an honest error or misconduct or plagiarism.3

Questions for your doctor

  • Is this result published in a peer-reviewed journal or is it still a preprint?
  • Has this study been retracted or has a correction been issued for it?

References

  1. 1
    PubMed Central (NLM). NIH Preprint Pilot. pmc.ncbi.nlm.nih.gov/about/nihpreprints/
    Health agencies & guidelines · Accessed 2026-10-08
  2. 2
    U.S. National Library of Medicine. Publication Characteristics (Publication Types) with Scope Notes. www.nlm.nih.gov/mesh/pubtypes.html
    Health agencies & guidelines · Accessed 2026-10-08
  3. 3
    U.S. National Library of Medicine. Errata, Retractions, and Other Linked Citations in PubMed. www.nlm.nih.gov/bsd/policy/errata.html
    Health agencies & guidelines · Accessed 2026-10-08
  4. 4
    Crossref. Retraction Watch (Crossref documentation). www.crossref.org/documentation/retrieve-metadata/retraction-watch/
    Educational & historical references · Accessed 2026-10-08
  5. 5
    Europe PMC. Europe PMC. europepmc.org/
    Educational & historical references · Accessed 2026-10-08

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